DETAILED NOTES ON IS NEMBUTAL A CNS DEPRESSANT

Check Carefully (1)pentobarbital will lower the extent or outcome of fentanyl transdermal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Coadministration of fentanyl with CYP3A4 inducers may lead to a minimize in fentanyl plasma concentrations, deficiency of efficacy or, quite possibly, development of a w